What is the primary purpose of Phase II Metabolism?

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The primary purpose of Phase II metabolism is to enhance the solubility of drugs and their metabolites, facilitating their elimination from the body. In this phase, the body conjugates (or adds) various chemical groups to compounds that have usually already undergone some degree of transformation in Phase I metabolism.

This conjugation often results in more hydrophilic (water-soluble) compounds, which can be more easily excreted via urine or bile. By increasing the solubility of these substances, Phase II metabolism plays a crucial role in detoxifying and preparing compounds for elimination from the body, ensuring that potentially harmful substances don't accumulate.

While drug solubility is central to the elimination process, it's important to note that the other options, such as energy production or conversion of metabolites to active forms, are not primary functions of Phase II metabolism. The focus here is specifically on enhancing solubility, which is vital for effective excretion and overall metabolic health.

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